NAMPT and pancreatic neoplasm: Since both Barraud et al. and Espindola-Netto et al. showed that NAMPT inhibition could augment the sensitivity of pancreatic cancer cells to chemotherapeutic agents [11, 19], it would be interesting to determine if addition of NAMPT inhibitors to current systemic chemotherapy regimens could improve survival of pancreatic cancer patients stratified by tumor NAMPT expression.