PSIP1 and esophageal squamous cell carcinoma: As shown in Figure 3A, when compared with mock‐transfected control cells, transfection of specific siRNAs (si‐p75‐1 and si‐p75‐2) induced obviously down‐regulated expression of LEDGF/p75 messenger RNA (mRNA) in all four ESCC cells, with si‐p75‐2 displaying stronger effect than si‐p75‐1.