No differences were evident between males and females, smokers (including ex‐smokers) and nonsmokers, diabetics and nondiabetics, and hypertensive and nonhypertensive subjects for p16INK4A expression (Supporting Information Figure S2a–d), and even though a trend was apparent, we found no differences between aortic disease, valvular disease, coronary artery disease and multiple other diseases for p16INK4A expression (Supporting Information Figure S2e). This evidence concerns the gene CDKN2A and coronary artery disorder.