A previously proposed hypothesis of antipsychotic-induced hyperprolactinemia as the cause for breast cancer has been shown to be inconclusive since hyperprolactinemia has also been observed in antipsychotic-naïve first-episode patients and even in prodromal stages, and several prolactin-elevating antipsychotics have been shown to have cancer-protection mechanisms [4]. The gene discussed is PRL; the disease is breast carcinoma.