Interestingly, pathways previously identified as important for establishment of chlamydial infection (Actin Nucleation by ARP-WASP Complex) [18] and subsequent growth (p53 signaling) [19, 20] were also over-represented as were genes involved in granulocyte adhesion and diapedesis, suggesting innate inflammatory signaling activation in some samples. This evidence concerns the gene TP53 and chlamydia trachomatis infectious disease.