In addition to colon cancer, FUT1 transgenic studies show enhanced vasculogenesis and gastrointestinal metastatic ability of pancreatic cancer cells (BxPC3), but greatly retarded the growth of hepatic cancer cells (HepG2) due to dramatic decrease in sLex expression, increase in Ley and Leb expression with failure to interact with endothelial E-selectin14,17,18. Here, FUT1 is linked to malignant colon neoplasm.