The HNRNPU (heterogeneous nuclear ribonucleoprotein U) and the FAM36A (family with sequence similarity 36, also known as COX20—cytochrome c oxidase assembly factor) genes, were proposed as good candidates for the epilepsy and ID phenotype within the 1q43-q44 microdeletion syndrome (Thierry et al., 2012; Poot and Kas, 2013; Leduc et al., 2017). The gene discussed is HNRNPU; the disease is epilepsy.