MAPT and Parkinson disease: Interestingly, all transcripts were expressed in the SN of healthy subjects, and all six lncRNAs exhibited remarkable under-expression in the SN of PD patients normalized relative to GAPDH levels (p < 0.01 for SNCA-AS1, AK127687; p < 0.001 for UCHL1-AS1, PINK1-AS1, AX747125, and MAPT-AS1) (Figure 3A).