Moreover, multiple evidences have shown that aberrant expression of TINCR is closely associated with various human cancers, for example, T-p Xu, et al. [8] reported that TINCR was overexpressed and regulated cell cycle progression and apoptosis via modulating CDKN1A/P21, KLF2 and CDKN2B/P15 expression in gastric cancer. This evidence concerns the gene CDKN1A and gastric cancer.