MKS1 and Meckel syndrome, type 1: A recent European study reported that the mean prevalence of MKS is 2.6 per 100,000 births (Barisic et al., 2015), but it can be much higher in certain populations, for example, in Finland, where MKS incidence is one in 9,000 livebirths (Salonen, Norio, Opitz, & Reynolds, 1984), with MKS1 gene mutations originally identified in the Finnish population (Kyttala et al., 2006).