In addition, IL-7 stimulation of T-ALL cells interferes with drug-induced apoptosis and cell cycle arrest induced by rapamycin [15], prednisolone [16], dexamethasone, and doxorubicin [17], whereas mutant IL-7R-mediated signaling contributes to resistance to glucocorticoids [18]. This evidence concerns the gene IL7R and acute lymphoblastic leukemia.