This may reflect the lack of IL-7-dependence in HPB-ALL cells (Fig. 3b) or the relatively mild inhibitory effect in D1 cells (Fig. 3d), as opposed to cell lines in which the antibody had a strong negative effect and that are well-known to depend on IL-7 signaling, as is the case of TAIL7 [33], or displaying endogenous IL-7R mutation, as is the case of DND41 [12]. The gene discussed is IL7; the disease is acute lymphoblastic leukemia.