Thus, in combination with the transcriptional genes regulated by telmisartan, the telmisartan network that ameliorated NASH in the livers of STAM mice, and which harbored the NAFLD pathway that was interconnected with the RAS and the PPAR-NFκB signaling pathways, was successfully generated. The gene discussed is NFKB1; the disease is metabolic dysfunction-associated steatohepatitis.