IL4 and neoplasm: In contrast to the coculture with tumor cells, neither MΦ-polarizing stimuli such as 100 ng/mL LPS (lipopolysaccharide) + 100 U/mL interferon-γ (IFNγ), 20 ng/mL interleukin-4 (IL-4), nor the resolution-phase stimulus resolvin D1 increased miR-375 levels in MΦ (Fig. 1d).