Analysis of database from the Cancer Genome Atlas (TCGA) and Molecular Taxonomy of Breast Cancer International Consortium (METABRIC), high levels of PFKP expression were observed in the malignant basal-like breast cancer patients and higher levels of CS expression was positively correlated with worse overall survival of breast cancer patients (Fig. 4i and Figure S5G-S5H). The gene discussed is PFKP; the disease is breast carcinoma.