TFE3 and renal cell carcinoma associated with Xp11.2 translocations/TFE3 gene fusions: All these resulted in gene fusions involving the Transcription Factor Binding to IGHM Enhancer 3 (TFE3) gene and Xp11.2 tRCC is characterized by overexpressed TFE3 fusion gene and affecting patients younger than 45 years with poor prognosis.