Furthermore, five of these seven ATP2B4 SNPs (minor frequency alleles: rs10900585-G, rs2365860-C, rs10900589-A, rs2365858-G and rs4951074-A) were associated with resistance against severe falciparum malaria in Western African populations in Ghana and Gambia [42], and rs10900585 has been associated with reduced malarial placental infection and related maternal anemia in Ghana [43]. Here, ATP2B4 is linked to Plasmodium falciparum malaria.