INS and type 1 diabetes mellitus: Therefore, in this exploratory study we compared overnight insulin and glucose profiles in children with type 1 diabetes, who received in random order either the sensor augmented pump (pre programmed–hourly- basal insulin rate, but with continuous glucose measurements, visualized on the insulin pump) or the closed-loop insulin delivery system, with a model-based algorithm, (variable -15 min- basal insulin rate, steered by the algorithm based on continuous glucose measurements).