AKT1 and melanoma: The most visible effect of melanoma cells treatment with single inhibitor on the protein expression level of p-Bcl-2 (S70) and p-Bcl-2 (T56) was observed after incubation with MEK inhibitor - AS-703026 or PI3K inhibitor - LY294002, slightly weaker being that for ERK1/2 inhibitor - U126 or AKT - MK-2206 (Fig.1).