In the microenvironment of human neuroblastoma, Gal‐3BP interacts with Galectin‐3 (Gal‐3) in bone marrow mesenchymal stem cells (BMMSC) and induces transcriptional upregulation of IL‐6, via the Gal‐3BP/Gal‐3/Ras/MEK/ERK signaling pathway.22, 23 These findings suggest that these two genes may collaboratively participate in the pathological process of cancer. Here, LGALS3 is linked to neuroblastoma.