RHOA and neoplasm: Atypical protein kinase C/NF‐κB signaling also plays a vital role in EMT, which induces tumor proliferation, migration, and invasion.33 Previous studies have reported that AKT can facilitate the nuclear entry of NF‐κB (p‐P65), which can then function to increase Snail and Slug expression and thus accelerate EMT.34 The exploration of RhoA was based on biological database predictions (such as String, PPI, etc), as well as screening of downstream proteins by Western blotting and PCR after Pard3 knockdown or overexpression.