RhoA (Ras homolog family member A) acts as a cancer suppressor gene and plays a significant role in tumor progression.8 Previous findings indicate that the Rho/ROCK pathway is actively involved in the regulation of glioma cell death.9 RhoA is also an important suppressor of EMT (Epithelial‐mesenchymal transition)10; the loss of RhoA is correlated with tumor grade and predicts a poor outcome in patient.11. Here, RHOA is linked to central nervous system cancer.