A score based on the expression of the 17 most informative genes (LSC17 score), which interestingly also included the GPR56 gene, was strongly associated with poor overall survival in several AML cohorts.15 To test whether GPR56 or CLL‐1 surface expression correlates with this LSC17 gene signature, we sorted CD34+38− leukemic cells according to their GPR56 as well as CLL‐1 surface levels (Supporting Information, Figure S2) and determined the expression of genes included in this LSC17 panel by quantitative RT‐PCR (qPCR). This evidence concerns the gene ADGRG1 and acute myeloid leukemia.