The results of a previous study revealed that Rab25 recycles β1 integrin from lysosomal degradation to the plasma membrane, extending the biological role of the recycled protein.25 BY Jeong reported that Rab25 induces β1 integrin expression, which activates the EGFR/VEGFA/VEGFR1/snail signalling axis, leading to EMT in ovarian cancer cells.8 Consistent with previous data, we observed that Rab25 associated with β1 integrin and mediated β1 integrin recycling to the plasma membrane to participate in biological activities. This evidence concerns the gene FLT1 and ovarian cancer.