Consistent with the tumour volume data, the tumour tissue samples from the PC9/ER/shRab25 and HCC827/ER/shRab25 groups expressed lower Rab25, β1 integrin, β‐catenin and ki‐67 protein levels than those from the PC9/ER/shctrl and HCC827/ER/shctrl groups (Figure 4E,F). Here, RAB25 is linked to neoplasm.