The differences in low hemoglobin (P=0.036), leukopenia (P=0.025), CRP (P=0.035), complement C3 (P=0.036), albumin (P=0.039), and anti-dsDNA antibody (P=0.043) were statistically significant between the two groups, while the differences in thrombocytopenia (P=0.917), ALT (P=0.247), serum creatinine (P=0.499), and anti-SM antibody (0.866) were not statistically significant (Table 3). The gene discussed is C3; the disease is Decreased total leukocyte count.