Poly (ethylene glycol)-b-poly (L-lysine)-b-poly (L-leucine) (PEG-PLL-PLLeu) polypeptide micelles was used for co-encapsulating Toll-like receptor agonist, STAT3 siRNA and OVA antigen to generate nanovaccine in OVA-transfected melanoma cell line (172). Here, STAT3 is linked to melanoma.