Our analysis, in accordance with previously published results, showed that dietary polyphenols downregulated MUC2 in Caco‐2/HT29‐MTX cocultured cells and may possibly alter its biosynthesis or secretion, which may be linked to gastrointestinal disease (Rakha et al., 2005; Van Klinken, Van der Wal, Einerhand, Büller, & Dekker, 1999). The gene discussed is MUC2; the disease is gastrointestinal disease.