Recently, we performed whole-genome sequencing (WGS) on a large cohort (n =183) of cutaneous (n = 140), acral (n = 35) and mucosal melanomas (n = 8), and SF3B1 (splicing factor 3B subunit 1) was identified as significantly mutated gene in mucosal melanoma [15]. Here, SF3B1 is linked to mucosal melanoma.