Potential miR-409-3p target genes have been previously reported; for example, Beclin-1 in colon cancer (Tan et al., 2016), radixin in gastric cancer (Zheng et al., 2012), and Ras suppressor 1 and stromal antigen 2 in prostate cancer (Josson et al., 2015). Here, BECN1 is linked to colonic neoplasm.