G6PD and hepatitis A virus infection: Through comparison of 18 cases of acute hepatitis A infection combined with G6PD deficiency and 18 cases of hepatitis A infection but with G6PD normal patients, Gotsman et al. 2 suggested that G6PD deficiency might impede the repair of hepatocytes damaged by viral hepatitis as a result of increased oxidative damage to hepatocytes because of glutathione depletion, thus causing liver malfunction.