CDH1 and neoplasm: In recent years, research findings suggest that EMT plays a major role in tumor metastasis, which may regulate mesothelial cell clearance and drive early dissemination into the peritoneal cavity [23].Moreover, EMT is a biologic process where cells lose their epithelial marker such as E-cadherin and obtain mesenchymal-like phenotype marker including Vimentin, which usually occurs in the initial stage of tumor metastasis.