Representative immunohistochemical CD34 staining of MM patients with high and low BM CX3CL1 levels is reported in Figure 2B. Similar to that observed with BM aspirates, we also found that BM soluble CX3CL1 levels significantly positively correlated with the number of BM PCs in bone biopsies (Figure 2C) (P = 0.0013, r = 0.58, Spearman’s correlation). The gene discussed is CX3CL1; the disease is Miyoshi myopathy.