Cx26 predicts a poor outcome for NSCLC in general, and a significantly worse prognosis in the LUAD subgroup (HR = 2.12), where patients with high Cx26 expression are predicted to live an average of 56 months less than those with low Cx26 expression (80 months vs. 136 months). The gene discussed is GJB2; the disease is non-small cell lung carcinoma.