IGFBP3 and cancer: ΔNp63 and IGFBP‐3 expression are inversely correlated in human SCC samples and decreased IGFBP3 expression is correlated with unfavourable prognosis in human cancers (Barbieri et al., 2005; Chang et al., 2002; Katsaros et al., 2001), implying a potential relevance of IGFBP3 suppression in SCC development.