IGF1 and head and neck squamous cell carcinoma: However, further studies are needed to clarify the clinical impact of the ∆Np63/IGF signaling, as contradictory findings on the prognostic impact of IGF signalling have been reported in HNSCC (Dale et al., 2015; Lara et al., 2011; Luo et al., 2014; Sun et al., 2011).