Such virus reactivation is reflected by increased and aberrant antibody responses against multiple EBV antigens.19, 20 Several prospective epidemiological studies are convinced that EBV antibodies can be elevated for several years prior to NPC diagnosis.21, 22, 23 Specific antibodies, immunoglobulin A (IgA) antibodies against EBV capsid antigens (VCA‐IgA), and nuclear antigen1 (EBNA1‐IgA) have been used to screen for NPC in endemic areas. This evidence concerns the gene CD79A and nasopharyngeal carcinoma.