HPCAL1 and brain neoplasm: The translocation capability of VSNL proteins from the cytoplasm to the subcellular membrane compartments, especially after an increase in the level of Ca2+ in cytoplasm, is due to the EF‐hand calcium‐binding motifs and the consensus N‐terminal myristoylation sequence.6, 20 Despite the dependence of HPCAL1 on Ca2+ in brain homogenates, few studies have demonstrated its influence on brain tumour.