Loss of E‐cadherin expression is associated with increased invasive and metastatic ability in a variety of tumours such as breast and lung tumours.15, 16 The link between loss of E‐cadherin and invasive tumour behavior might be related to the induction of epithelial‐to‐mesenchymal transition (EMT) commonly observed in the most advanced phases of these tumours. This evidence concerns the gene CDH1 and neoplasm.