The aneurysm prone aortic tissues of the DMSO-treated mice contained PI-positive necrotic cells, elevated levels of phospho-MLKL, as well as terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL)-positive apoptotic cells and CD68-positive macrophages (Fig. 7c–f). Here, MLKL is linked to aneurysm.