SHBG and heart disorder: One small mendelian randomisation study (n=1454) in men that used rs1799941 from the SHBG gene to predict testosterone found no association of testosterone with myocardial infarction.50 This finding corresponds with our conclusion that there is no clear association of testosterone predicted by SHBG gene region variants with myocardial infarction, and with the results for ischaemic heart disease in our previous mendelian randomisation study.31