E2F4 and acute respiratory distress syndrome: Reduced deposition of collagen was observed after intervention with either mBM-MSC-p130 or mBM-MSC-E2F4 compared with the ARDS group (p < 0.05), but the decreased deposition of collagen observed in the LPS+mBM-MSC-p130 and LPS+mBM-MSC-E2F4 groups was more significant than that observed in the LPS+mBM-MSC-NC group (p < 0.05) (Fig. 6a, b).