ACE and diabetes mellitus: After age, the presence of comorbid diabetes and use of MRAs at the time of the index HK event were associated with the highest ORs for recurrent HK (1.86 [95% CI, 1.81–1.91] and 1.74 [95% CI, 1.64–1.85], respectively); ACE inhibitor and ARB use at the time of the index HK event was also associated with recurrent HK.