Our exploratory analyses found interactions between polymorphisms in the fatty acid metabolic pathway (LPCAT1 s7737692 and SLC25A20 rs7623023) and polymorphisms that have been found to interact with NSAID/aspirin (CCAT2 rs6983267 and TP53 rs1042522) on one hand and intake of red and processed meat on the other in relation to risk of CRC. The gene discussed is SLC25A20; the disease is colorectal carcinoma.