ECE1 and candidiasis: Our future studies will focus on elucidating the extent to which C. albicans hyphae and Candidalysin contribute to increasing host angiogenesis in the murine systemic candidiasis model by using existing ece1 mutants that make hyphae but do not secrete Candidalysin and, if necessary, by constructing yeast-locked strains that produce the toxin.