For mRNAs, the expression levels of DDX11, E2F1, NPTX1, and PLXNA4 were significantly lower in nintedanib-treated IPF fibroblasts than in controls, and the expression levels of SLC25A23 were significantly higher in nintedanib-treated IPF fibroblasts than in controls (Figure 7A). This evidence concerns the gene SLC25A23 and idiopathic pulmonary fibrosis.