At least 21 of these are clearly suspect as they have 3 stars in ClinVar indicating review by an “expert panel.” 20 are variations in well‐known oncogenes MLH1, MSH2, MSH6, BRCA1, and one in the MYH7 gene is well known to be associated with cardiomyopathy. The gene discussed is MSH2; the disease is cardiomyopathy.