In 26 patients with AML, the recurrent translocations BCR-ABL1, RUNX1-RUNX1T1, CBFB-MYH11, PML-RARA, SET-NUP24, ZBTB16-RARA, KMT2A-MLLT3, and FUS-ERG were identified by RT-PCR. The gene discussed is KMT2A; the disease is acute myeloid leukemia.