Moreover, several studies have also shown that overexpression of MMP‐2 is associated with the progression of multiple cancers, as well as metastases.50, 51 Inhibiting the expression of MMP‐2 can significantly suppress tumour progression.52 Therefore, the IR tyrosine kinase may serve as a promising therapeutic target for preventing pancreatic carcinogenesis. The gene discussed is MMP2; the disease is neoplasm.