We selected PPARG rs3856806 C>T, PPARGC1A rs2970847 C>T, rs8192678 C>T, rs3736265 G>A, and PPARGC1B rs7732671 G>C and rs17572019 G>A SNPs to determine the relationship between their variants and CRC risk in an Eastern Chinese Han population. The gene discussed is PPARGC1B; the disease is colorectal carcinoma.