Cyclin-dependent kinase 1 (CDK1) is a protein that regulates the cell cycle, which belongs to a serine/threonine kinase family (Malumbres and Barbacid, 2009); previous studies have proved that CDK1 acted as a key regulator for cell cycle (Yang et al., 2016), and its expression increases in several cancer growths, such as colon carcinoma (Meyer et al., 2009), non-small cell lung cancer tumor (Kim et al., 2008; Zhang et al., 2011); There are also researches that identify that inhibition of CDK1 can suppress the proliferation and migration of some tumor cells (Zhang et al., 2015). This evidence concerns the gene MARK2 and cancer.