The results of this analysis revealed that a number of pathways already enriched in the comparison of CRC patients with their non-CRC counterparts (Figures 2B,C) (“Cell-to-cell adhesion,” “Cadherin binding involved in cell-cell adhesion,” “Extracellular matrix organization,” “Glucagon signaling pathway,” “Platelet activation”) were found further enriched when directly comparing ObCRC with NwCRC patients, highlighting a stronger dysregulation of these processes in the obese background. This evidence concerns the gene GCG and colorectal carcinoma.