In turn, large mitochondria produce more ATP than smaller ones (Sun et al., 2014), which in turn may increase the motor activity of Drosophila. Higher levels of Nix protein, a mitochondrial autophagy receptor, likewise increases ATP levels in strains that are also genetic models of Parkinson’s disease and shows that ATP levels depend on the quality of mitophagy (Koentjoro et al., 2017). The gene discussed is BNIP3L; the disease is Parkinson disease.