Moreover, importantly, stroke has an inflammatory component, and some inflammatory inducers or mediators (e.g., lipopolysaccharide or interleukin 6) have been found to increase the expression of hepcidin in astrocytes, microglia, or neurons (for a recent review see Vela, 2018), although the effect on neurons is usually weaker (Ma et al., 2018). Here, HAMP is linked to stroke disorder.